Welcome to Epistem Pharmacogenomics
Epistem Pharmacogenomics provides high quality biomarker and personalised medicine Information to pharmaceutical and biotechnology companies from very limited quantities of RNA (down to a single cell input). We specialise in advancing drug development programs for oncology, inflammatory and fibrotic disease indications through our innovative plucked hair analysis and laser capture microdissection techniques as well as offering GCLP accredited laboratory gene expression and DNA genotyping services. In addition to our expertise in assessing limited quantities of RNA, we also have extensive experience in developing patient stratification companion diagnostic assays using our point of care Genedrive® platform.
Epistem's proprietary amplification technique, RNA-Amp™, allows robust gene expression information to be derived from as little as a single cell input
Epistem provides a unique plucked hair biomarker platform to drug development companies targeting intracellular signalling pathways in oncology and other therapeutic areas.
Epistem offers Laser Capture Microdissection (LCM) services and subsequent gene expression and DNA genotype analysis. This technique is an ideal method for obtaining molecular analysis of specific cell populations.
Epistem provides global (microarray) and focused (qPCR) GCLP accredited mRNA and miRNA gene expression profiling services.
Epistem provides laboratory GCLP (microarray and qPCR) and Point of Care (Genedrive®) ISO13485 accredited DNA genotyping services.
Epistem Pharmacogenomics amplification technology is ideally suited for assessing fluid or tissue based samples that have limited quantities of RNA.